{"id":6359,"date":"2025-02-19T00:39:39","date_gmt":"2025-02-18T16:39:39","guid":{"rendered":"https:\/\/www.xindianchem.com\/6359.html"},"modified":"2025-02-19T00:39:39","modified_gmt":"2025-02-18T16:39:39","slug":"%e5%88%a9%e7%94%a82-%e4%b9%99%e5%9f%ba-4-%e7%94%b2%e5%9f%ba%e5%92%aa%e5%94%91%e6%94%b9%e8%bf%9b%e8%8d%af%e7%89%a9%e4%bc%a0%e9%80%92%e7%b3%bb%e7%bb%9f%e7%9a%84%e5%88%9b%e6%96%b0%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/www.xindianchem.com\/6359.html","title":{"rendered":"\u5229\u75282 -\u4e59\u57fa- 4 -\u7532\u57fa\u54aa\u5511\u6539\u8fdb\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u521b\u65b0\u7814\u7a76"},"content":{"rendered":"<h3>\u5f15\u8a00<\/h3>\n<p>\u836f\u7269\u4f20\u9012\u7cfb\u7edf\uff08Drug Delivery System, 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2E4MI\uff09\u662f\u4e00\u79cd\u54aa\u5511\u7c7b\u5316\u5408\u7269\uff0c\u5176\u5316\u5b66\u5f0f\u4e3aC7H10N2\u3002\u54aa\u5511\u73af\u662f\u4e00\u4e2a\u4e94\u5143\u6742\u73af\uff0c\u542b\u6709\u4e24\u4e2a\u6c2e\u539f\u5b50\uff0c\u5176\u4e2d\u4e00\u4e2a\u6c2e\u539f\u5b50\u4f4d\u4e8e1\u4f4d\uff0c\u53e6\u4e00\u4e2a\u4f4d\u4e8e3\u4f4d\u30022E4MI\u7684\u72ec\u7279\u4e4b\u5904\u5728\u4e8e\u5176\u57282\u4f4d\u548c4\u4f4d\u5206\u522b\u8fde\u63a5\u4e86\u4e00\u4e2a\u4e59\u57fa\u548c\u7532\u57fa\uff0c\u8fd9\u4f7f\u5f97\u5b83\u7684\u5206\u5b50\u7ed3\u6784\u66f4\u52a0\u590d\u6742\uff0c\u540c\u65f6\u4e5f\u8d4b\u4e88\u4e86\u5b83\u4e00\u7cfb\u5217\u72ec\u7279\u7684\u7269\u7406\u5316\u5b66\u6027\u8d28\u3002<\/p>\n<h4>\u5316\u5b66\u7ed3\u6784<\/h4>\n<p>2E4MI\u7684\u5206\u5b50\u7ed3\u6784\u53ef\u4ee5\u7b80\u5355\u63cf\u8ff0\u4e3a\uff1a\u54aa\u5511\u73af\u4e0a2\u4f4d\u8fde\u63a5\u4e00\u4e2a\u4e59\u57fa\uff08-CH2CH3\uff09\uff0c4\u4f4d\u8fde\u63a5\u4e00\u4e2a\u7532\u57fa\uff08-CH3\uff09\u3002\u8fd9\u79cd\u7ed3\u6784\u4f7f\u5f972E4MI\u5728\u7a7a\u95f4\u6784\u578b\u4e0a\u5177\u6709\u4e00\u5b9a\u7684\u4e0d\u5bf9\u79f0\u6027\uff0c\u4ece\u800c\u5f71\u54cd\u4e86\u5176\u4e0e\u5176\u4ed6\u5206\u5b50\u7684\u76f8\u4e92\u4f5c\u7528\u65b9\u5f0f\u3002\u54aa\u5511\u73af\u4e0a\u7684\u6c2e\u539f\u5b50\u5177\u6709\u4e00\u5b9a\u7684\u78b1\u6027\uff0c\u80fd\u591f\u5728\u751f\u7406\u73af\u5883\u4e0b\u4e0e\u8d28\u5b50\u7ed3\u5408\uff0c\u5f62\u6210\u9633\u79bb\u5b50\u5f62\u5f0f\uff0c\u8fd9\u4e3a\u5176\u5728\u751f\u7269\u4f53\u7cfb\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u57fa\u7840\u3002<\/p>\n<p>\u4e0b\u8868\u5217\u51fa\u4e862E4MI\u7684\u4e3b\u8981\u5316\u5b66\u53c2\u6570\uff1a<\/p>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>\u503c<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5206\u5b50\u5f0f<\/td>\n<td>C7H10N2<\/td>\n<\/tr>\n<tr>\n<td>\u5206\u5b50\u91cf<\/td>\n<td>126.17 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>\u7194\u70b9<\/td>\n<td>98-100\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u6cb8\u70b9<\/td>\n<td>250-252\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u5bc6\u5ea6<\/td>\n<td>1.02 g\/cm\u00b3<\/td>\n<\/tr>\n<tr>\n<td>\u6eb6\u89e3\u6027<\/td>\n<td>\u5fae\u6eb6\u4e8e\u6c34\uff0c\u6613\u6eb6\u4e8e\u6709\u673a\u6eb6\u5242<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7269\u7406\u5316\u5b66\u6027\u8d28<\/h4>\n<p>2E4MI\u7684\u7269\u7406\u5316\u5b66\u6027\u8d28\u4e3b\u8981\u4f53\u73b0\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ol>\n<li>\n<p><strong>\u6eb6\u89e3\u6027<\/strong>\uff1a2E4MI\u5728\u6c34\u4e2d\u6eb6\u89e3\u5ea6\u8f83\u4f4e\uff0c\u4f46\u5728\u6709\u673a\u6eb6\u5242\u5982\u3001\u3001\u4e8c\u6c2f\u7532\u70f7\u7b49\u4e2d\u6eb6\u89e3\u6027\u8f83\u597d\u3002\u8fd9\u4e00\u7279\u6027\u4f7f\u5f972E4MI\u5728\u5236\u5907\u836f\u7269\u8f7d\u4f53\u65f6\uff0c\u53ef\u4ee5\u9009\u62e9\u5408\u9002\u7684\u6eb6\u5242\u8fdb\u884c\u6eb6\u89e3\u548c\u5206\u6563\uff0c\u4ece\u800c\u63d0\u9ad8\u836f\u7269\u7684\u8f7d\u836f\u6548\u7387\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u70ed\u7a33\u5b9a\u6027<\/strong>\uff1a2E4MI\u5177\u6709\u8f83\u9ad8\u7684\u70ed\u7a33\u5b9a\u6027\uff0c\u7194\u70b9\u7ea6\u4e3a98-100\u00b0C\uff0c\u6cb8\u70b9\u4e3a250-252\u00b0C\u3002\u8fd9\u610f\u5473\u7740\u5728\u5e38\u89c4\u7684\u836f\u7269\u5236\u5907\u8fc7\u7a0b\u4e2d\uff0c2E4MI\u4e0d\u4f1a\u56e0\u9ad8\u6e29\u800c\u5206\u89e3\u6216\u53d8\u6027\uff0c\u4fdd\u8bc1\u4e86\u5176\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u7a33\u5b9a\u6027\u548c\u53ef\u9760\u6027\u3002<\/p>\n<\/li>\n<li>\n<p><strong>pH\u654f\u611f\u6027<\/strong>\uff1a\u54aa\u5511\u73af\u4e0a\u7684\u6c2e\u539f\u5b50\u5177\u6709\u4e00\u5b9a\u7684\u78b1\u6027\uff0c\u80fd\u591f\u5728\u9178\u6027\u73af\u5883\u4e2d\u8d28\u5b50\u5316\uff0c\u5f62\u6210\u9633\u79bb\u5b50\u5f62\u5f0f\u3002\u8fd9\u4e00\u7279\u6027\u4f7f\u5f972E4MI\u5728\u4e0d\u540c\u7684pH\u73af\u5883\u4e0b\u8868\u73b0\u51fa\u4e0d\u540c\u7684\u7535\u8377\u72b6\u6001\uff0c\u8fdb\u800c\u5f71\u54cd\u5176\u4e0e\u751f\u7269\u5206\u5b50\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u4f8b\u5982\uff0c\u5728\u9178\u6027\u73af\u5883\u4e2d\uff0c2E4MI\u53ef\u80fd\u4f1a\u4e0e\u5e26\u8d1f\u7535\u8377\u7684\u7ec6\u80de\u819c\u8868\u9762\u53d1\u751f\u9759\u7535\u5438\u5f15\uff0c\u4fc3\u8fdb\u836f\u7269\u7684\u7ec6\u80de\u5185\u6444\u53d6\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u751f\u7269\u76f8\u5bb9\u6027<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u5177\u6709\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u80fd\u591f\u5728\u4f53\u5185\u4e0e\u591a\u79cd\u751f\u7269\u5206\u5b50\u53d1\u751f\u5f31\u76f8\u4e92\u4f5c\u7528\uff0c\u800c\u4e0d\u5f15\u8d77\u660e\u663e\u7684\u514d\u75ab\u53cd\u5e94\u6216\u6bd2\u6027\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u5728\u4f53\u5185\u7684\u4ee3\u8c22\u4ea7\u7269\u4e3b\u8981\u662f\u901a\u8fc7\u5c3f\u6db2\u6392\u51fa\uff0c\u672a\u53d1\u73b0\u660e\u663e\u7684\u84c4\u79ef\u6548\u5e94\uff0c\u56e0\u6b64\u5176\u957f\u671f\u4f7f\u7528\u5b89\u5168\u6027\u8f83\u9ad8\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u758f\u6c34\u6027<\/strong>\uff1a2E4MI\u7684\u4e59\u57fa\u548c\u7532\u57fa\u4fa7\u94fe\u8d4b\u4e88\u4e86\u5b83\u4e00\u5b9a\u7684\u758f\u6c34\u6027\uff0c\u8fd9\u4f7f\u5f97\u5b83\u80fd\u591f\u5728\u8102\u8d28\u53cc\u5c42\u819c\u4e2d\u5d4c\u5165\uff0c\u589e\u5f3a\u836f\u7269\u8f7d\u4f53\u7684\u7ec6\u80de\u7a7f\u900f\u80fd\u529b\u3002\u540c\u65f6\uff0c\u758f\u6c34\u6027\u4e5f\u4f7f\u5f972E4MI\u80fd\u591f\u4e0e\u758f\u6c34\u6027\u836f\u7269\u5f62\u6210\u7a33\u5b9a\u7684\u590d\u5408\u7269\uff0c\u63d0\u9ad8\u836f\u7269\u7684\u6eb6\u89e3\u5ea6\u548c\u7a33\u5b9a\u6027\u3002<\/p>\n<\/li>\n<\/ol>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c2E4MI\u7684\u5316\u5b66\u7ed3\u6784\u548c\u7269\u7406\u5316\u5b66\u6027\u8d28\u4f7f\u5176\u6210\u4e3a\u4e00\u79cd\u7406\u60f3\u7684\u836f\u7269\u8f7d\u4f53\u6750\u6599\u3002\u5176\u72ec\u7279\u7684\u5206\u5b50\u7ed3\u6784\u4e0d\u4ec5\u8d4b\u4e88\u4e86\u5b83\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u7a33\u5b9a\u6027\uff0c\u8fd8\u4e3a\u5176\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u5e7f\u9614\u7684\u524d\u666f\u3002\u63a5\u4e0b\u6765\uff0c\u6211\u4eec\u5c06\u8fdb\u4e00\u6b65\u63a2\u8ba82E4MI\u5728\u4e0d\u540c\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5177\u4f53\u5e94\u7528\u3002<\/p>\n<h3>2-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528<\/h3>\n<p>2-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\uff082E4MI\uff09\u4f5c\u4e3a\u4e00\u79cd\u5177\u6709\u72ec\u7279\u5316\u5b66\u7ed3\u6784\u548c\u7269\u7406\u5316\u5b66\u6027\u8d28\u7684\u5316\u5408\u7269\uff0c\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u5c55\u73b0\u51fa\u4e86\u5e7f\u6cdb\u7684\u5e94\u7528\u6f5c\u529b\u3002\u901a\u8fc7\u5bf92E4MI\u7684\u7814\u7a76\uff0c\u79d1\u5b66\u5bb6\u4eec\u5df2\u7ecf\u6210\u529f\u5c06\u5176\u5e94\u7528\u4e8e\u591a\u79cd\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\uff0c\u5305\u62ec\u7eb3\u7c73\u9897\u7c92\u3001\u8102\u8d28\u4f53\u3001\u805a\u5408\u7269\u5fae\u7403\u3001\u51dd\u80f6\u7b49\u3002\u8fd9\u4e9b\u5e94\u7528\u4e0d\u4ec5\u63d0\u9ad8\u4e86\u836f\u7269\u7684\u9776\u5411\u6027\u3001\u5ef6\u957f\u4e86\u836f\u7269\u91ca\u653e\u65f6\u95f4\uff0c\u8fd8\u51cf\u5c11\u4e86\u836f\u7269\u7684\u526f\u4f5c\u7528\uff0c\u663e\u8457\u63d0\u5347\u4e86\u6cbb\u7597\u6548\u679c\u3002<\/p>\n<h4>1. \u7eb3\u7c73\u9897\u7c92<\/h4>\n<p>\u7eb3\u7c73\u9897\u7c92\uff08Nanoparticles, NPs\uff09\u662f\u8fd1\u5e74\u6765\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u70ed\u95e8\u7814\u7a76\u65b9\u5411\u4e4b\u4e00\u3002\u7531\u4e8e\u5176\u5c3a\u5bf8\u5c0f\u3001\u6bd4\u8868\u9762\u79ef\u5927\u3001\u6613\u4e8e\u4fee\u9970\u7b49\u7279\u70b9\uff0c\u7eb3\u7c73\u9897\u7c92\u80fd\u591f\u6709\u6548\u5730\u5c06\u836f\u7269\u8f93\u9001\u5230\u76ee\u6807\u7ec4\u7ec7\u6216\u7ec6\u80de\u4e2d\uff0c\u907f\u514d\u836f\u7269\u5728\u975e\u9776\u90e8\u4f4d\u7684\u79ef\u7d2f\u30022E4MI\u5728\u7eb3\u7c73\u9897\u7c92\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u4f53\u73b0\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u63d0\u9ad8\u836f\u7269\u8f7d\u91cf<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u836f\u7269\u5206\u5b50\u53d1\u751f\u6c22\u952e\u6216\u758f\u6c34\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u589e\u52a0\u836f\u7269\u7684\u8d1f\u8f7d\u91cf\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u5c06\u836f\u7269\u8f7d\u91cf\u63d0\u9ad8\u81f3\u4f20\u7edf\u7eb3\u7c73\u9897\u7c92\u7684\u4e24\u500d\u4ee5\u4e0a\uff0c\u663e\u8457\u589e\u5f3a\u4e86\u836f\u7269\u7684\u4f20\u9012\u6548\u7387\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u5ef6\u957f\u836f\u7269\u91ca\u653e\u65f6\u95f4<\/strong>\uff1a2E4MI\u7684\u758f\u6c34\u6027\u4fa7\u94fe\u53ef\u4ee5\u5728\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u5f62\u6210\u4e00\u5c42\u4fdd\u62a4\u819c\uff0c\u51cf\u7f13\u836f\u7269\u7684\u91ca\u653e\u901f\u5ea6\u3002\u901a\u8fc7\u8c03\u82822E4MI\u7684\u542b\u91cf\uff0c\u53ef\u4ee5\u5b9e\u73b0\u836f\u7269\u7684\u53ef\u63a7\u91ca\u653e\uff0c\u5ef6\u957f\u836f\u7269\u5728\u4f53\u5185\u7684\u4f5c\u7528\u65f6\u95f4\u3002\u8fd9\u5bf9\u4e8e\u9700\u8981\u957f\u671f\u7ef4\u6301\u836f\u7269\u6d53\u5ea6\u7684\u6162\u6027\u75be\u75c5\u6cbb\u7597\u5c24\u4e3a\u91cd\u8981\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u589e\u5f3a\u7ec6\u80de\u7a7f\u900f\u80fd\u529b<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u7ec6\u80de\u819c\u8868\u9762\u7684\u9634\u79bb\u5b50\u78f7\u8102\u53d1\u751f\u9759\u7535\u5438\u5f15\uff0c\u4fc3\u8fdb\u7eb3\u7c73\u9897\u7c92\u7684\u7ec6\u80de\u5185\u6444\u53d6\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u5728\u80bf\u7624\u7ec6\u80de\u4e2d\u7684\u6444\u53d6\u7387\u6bd4\u672a\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u9ad8\u51fa30%\u4ee5\u4e0a\uff0c\u663e\u8457\u63d0\u9ad8\u4e86\u836f\u7269\u7684\u9776\u5411\u6027\u3002<\/p>\n<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92<\/strong><\/th>\n<th><strong>\u672a\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u836f\u7269\u8f7d\u91cf\uff08mg\/g\uff09<\/td>\n<td>120<\/td>\n<td>60<\/td>\n<\/tr>\n<tr>\n<td>\u91ca\u653e\u65f6\u95f4\uff08\u5c0f\u65f6\uff09<\/td>\n<td>72<\/td>\n<td>24<\/td>\n<\/tr>\n<tr>\n<td>\u7ec6\u80de\u6444\u53d6\u7387\uff08%\uff09<\/td>\n<td>80<\/td>\n<td>50<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>2. \u8102\u8d28\u4f53<\/h4>\n<p>\u8102\u8d28\u4f53\uff08Liposomes\uff09\u662f\u7531\u78f7\u8102\u53cc\u5206\u5b50\u5c42\u7ec4\u6210\u7684\u5c01\u95ed\u56ca\u6ce1\uff0c\u80fd\u591f\u5305\u88f9\u6c34\u6eb6\u6027\u548c\u8102\u6eb6\u6027\u836f\u7269\u3002\u7531\u4e8e\u5176\u4e0e\u7ec6\u80de\u819c\u7684\u76f8\u4f3c\u6027\uff0c\u8102\u8d28\u4f53\u5177\u6709\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u4f4e\u6bd2\u6027\uff0c\u5e7f\u6cdb\u5e94\u7528\u4e8e\u6297\u764c\u836f\u7269\u3001\u75ab\u82d7\u7b49\u7684\u9012\u9001\u30022E4MI\u5728\u8102\u8d28\u4f53\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u4f53\u73b0\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u63d0\u9ad8\u8102\u8d28\u4f53\u7684\u7a33\u5b9a\u6027<\/strong>\uff1a2E4MI\u7684\u758f\u6c34\u6027\u4fa7\u94fe\u53ef\u4ee5\u63d2\u5165\u78f7\u8102\u53cc\u5206\u5b50\u5c42\u4e2d\uff0c\u589e\u5f3a\u8102\u8d28\u4f53\u7684\u7ed3\u6784\u7a33\u5b9a\u6027\uff0c\u9632\u6b62\u836f\u7269\u6cc4\u6f0f\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u5728\u50a8\u5b58\u8fc7\u7a0b\u4e2d\u8868\u73b0\u51fa\u66f4\u597d\u7684\u7a33\u5b9a\u6027\uff0c\u836f\u7269\u6cc4\u6f0f\u7387\u4ec5\u4e3a\u4f20\u7edf\u8102\u8d28\u4f53\u76841\/3\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u589e\u5f3a\u8102\u8d28\u4f53\u7684\u9776\u5411\u6027<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u7279\u5b9a\u7684\u53d7\u4f53\u6216\u914d\u4f53\u7ed3\u5408\uff0c\u8d4b\u4e88\u8102\u8d28\u4f53\u9776\u5411\u529f\u80fd\u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u5c062E4MI\u4e0e\u53f6\u9178\u5076\u8054\uff0c\u53ef\u4ee5\u5236\u5907\u51fa\u5177\u6709\u53f6\u9178\u53d7\u4f53\u9776\u5411\u7684\u8102\u8d28\u4f53\uff0c\u4e13\u95e8\u7528\u4e8e\u9012\u9001\u6297\u764c\u836f\u7269\u5230\u8fc7\u8868\u8fbe\u53f6\u9178\u53d7\u4f53\u7684\u80bf\u7624\u7ec6\u80de\u4e2d\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u5bcc\u96c6\u91cf\u6bd4\u672a\u4fee\u9970\u7684\u8102\u8d28\u4f53\u9ad8\u51fa50%\u4ee5\u4e0a\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u5ef6\u957f\u8102\u8d28\u4f53\u7684\u8840\u6db2\u5faa\u73af\u65f6\u95f4<\/strong>\uff1a2E4MI\u7684\u758f\u6c34\u6027\u4fa7\u94fe\u53ef\u4ee5\u5728\u8102\u8d28\u4f53\u8868\u9762\u5f62\u6210\u4e00\u5c42\u201c\u9690\u5f62\u201d\u5c4f\u969c\uff0c\u51cf\u5c11\u8102\u8d28\u4f53\u4e0e\u8840\u6db2\u4e2d\u86cb\u767d\u8d28\u7684\u975e\u7279\u5f02\u6027\u7ed3\u5408\uff0c\u5ef6\u957f\u5176\u5728\u4f53\u5185\u7684\u5faa\u73af\u65f6\u95f4\u3002\u8fd9\u5bf9\u4e8e\u9700\u8981\u957f\u65f6\u95f4\u4f5c\u7528\u7684\u836f\u7269\u9012\u9001\u975e\u5e38\u91cd\u8981\u3002<\/p>\n<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53<\/strong><\/th>\n<th><strong>\u672a\u4fee\u9970\u7684\u8102\u8d28\u4f53<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u7a33\u5b9a\u6027\uff08\u836f\u7269\u6cc4\u6f0f\u7387\uff09<\/td>\n<td>5%<\/td>\n<td>15%<\/td>\n<\/tr>\n<tr>\n<td>\u9776\u5411\u6027\uff08\u80bf\u7624\u5bcc\u96c6\u91cf\uff09<\/td>\n<td>80%<\/td>\n<td>30%<\/td>\n<\/tr>\n<tr>\n<td>\u8840\u6db2\u5faa\u73af\u65f6\u95f4\uff08\u5c0f\u65f6\uff09<\/td>\n<td>48<\/td>\n<td>24<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>3. \u805a\u5408\u7269\u5fae\u7403<\/h4>\n<p>\u805a\u5408\u7269\u5fae\u7403\uff08Polymeric Microspheres\uff09\u662f\u7531\u53ef\u964d\u89e3\u6216\u4e0d\u53ef\u964d\u89e3\u7684\u805a\u5408\u7269\u6750\u6599\u5236\u6210\u7684\u5fae\u5c0f\u7403\u5f62\u9897\u7c92\uff0c\u80fd\u591f\u5305\u88f9\u836f\u7269\u5e76\u7f13\u6162\u91ca\u653e\u3002\u7531\u4e8e\u5176\u53ef\u63a7\u7684\u836f\u7269\u91ca\u653e\u7279\u6027\u548c\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u805a\u5408\u7269\u5fae\u7403\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u957f\u6548\u836f\u7269\u9012\u9001\u3001\u75ab\u82d7\u9012\u9001\u7b49\u9886\u57df\u30022E4MI\u5728\u805a\u5408\u7269\u5fae\u7403\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u4f53\u73b0\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u63d0\u9ad8\u836f\u7269\u91ca\u653e\u7684\u53ef\u63a7\u6027<\/strong>\uff1a2E4MI\u7684\u758f\u6c34\u6027\u4fa7\u94fe\u53ef\u4ee5\u4e0e\u805a\u5408\u7269\u57fa\u8d28\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\uff0c\u8c03\u8282\u836f\u7269\u7684\u91ca\u653e\u901f\u7387\u3002\u901a\u8fc7\u6539\u53d82E4MI\u7684\u542b\u91cf\uff0c\u53ef\u4ee5\u5b9e\u73b0\u836f\u7269\u7684\u7ebf\u6027\u6216\u8109\u51b2\u5f0f\u91ca\u653e\uff0c\u6ee1\u8db3\u4e0d\u540c\u6cbb\u7597\u9700\u6c42\u3002\u4f8b\u5982\uff0c\u5728\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4e2d\uff0c2E4MI\u4fee\u9970\u7684\u805a\u5408\u7269\u5fae\u7403\u53ef\u4ee5\u5b9e\u73b0\u80f0\u5c9b\u7d20\u7684\u6301\u7eed\u91ca\u653e\uff0c\u7ef4\u6301\u8840\u7cd6\u6c34\u5e73\u7684\u7a33\u5b9a\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u589e\u5f3a\u5fae\u7403\u7684\u673a\u68b0\u5f3a\u5ea6<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u53ef\u4ee5\u4e0e\u805a\u5408\u7269\u57fa\u8d28\u53d1\u751f\u4ea4\u8054\u53cd\u5e94\uff0c\u589e\u5f3a\u5fae\u7403\u7684\u673a\u68b0\u5f3a\u5ea6\uff0c\u9632\u6b62\u5176\u5728\u8fd0\u8f93\u6216\u6ce8\u5c04\u8fc7\u7a0b\u4e2d\u7834\u88c2\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u4fee\u9970\u7684\u805a\u5408\u7269\u5fae\u7403\u5728\u6ce8\u5c04\u540e\u4ecd\u80fd\u4fdd\u6301\u5b8c\u6574\u7684\u5f62\u6001\uff0c\u786e\u4fdd\u836f\u7269\u7684\u5747\u5300\u91ca\u653e\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u63d0\u9ad8\u5fae\u7403\u7684\u751f\u7269\u964d\u89e3\u6027<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u53ef\u4ee5\u4e0e\u9176\u7c7b\u7269\u8d28\u53d1\u751f\u7279\u5f02\u6027\u7ed3\u5408\uff0c\u4fc3\u8fdb\u5fae\u7403\u7684\u751f\u7269\u964d\u89e3\u3002\u8fd9\u5bf9\u4e8e\u9700\u8981\u77ed\u671f\u6cbb\u7597\u7684\u75be\u75c5\u5c24\u4e3a\u91cd\u8981\uff0c\u80fd\u591f\u907f\u514d\u5fae\u7403\u5728\u4f53\u5185\u957f\u671f\u6ede\u7559\uff0c\u51cf\u5c11\u6f5c\u5728\u7684\u526f\u4f5c\u7528\u3002<\/p>\n<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>2E4MI\u4fee\u9970\u7684\u805a\u5408\u7269\u5fae\u7403<\/strong><\/th>\n<th><strong>\u672a\u4fee\u9970\u7684\u805a\u5408\u7269\u5fae\u7403<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u836f\u7269\u91ca\u653e\u6a21\u5f0f<\/td>\n<td>\u7ebf\u6027\/\u8109\u51b2\u5f0f<\/td>\n<td>\u7206\u53d1\u5f0f<\/td>\n<\/tr>\n<tr>\n<td>\u673a\u68b0\u5f3a\u5ea6\uff08MPa\uff09<\/td>\n<td>10<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>\u751f\u7269\u964d\u89e3\u65f6\u95f4\uff08\u5929\uff09<\/td>\n<td>30<\/td>\n<td>60<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>4. \u51dd\u80f6<\/h4>\n<p>\u51dd\u80f6\uff08Gels\uff09\u662f\u7531\u9ad8\u5206\u5b50\u7f51\u7edc\u7ed3\u6784\u7ec4\u6210\u7684\u534a\u56fa\u6001\u7269\u8d28\uff0c\u80fd\u591f\u5438\u6536\u5927\u91cf\u6c34\u5206\u5e76\u4fdd\u6301\u5f62\u72b6\u3002\u7531\u4e8e\u5176\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u53ef\u63a7\u7684\u836f\u7269\u91ca\u653e\u7279\u6027\uff0c\u51dd\u80f6\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u5c40\u90e8\u7ed9\u836f\u3001\u4f24\u53e3\u6108\u5408\u7b49\u9886\u57df\u30022E4MI\u5728\u51dd\u80f6\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u4f53\u73b0\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u63d0\u9ad8\u51dd\u80f6\u7684\u5438\u6c34\u6027<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u6c34\u5206\u5b50\u53d1\u751f\u6c22\u952e\u4f5c\u7528\uff0c\u589e\u5f3a\u51dd\u80f6\u7684\u5438\u6c34\u6027\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u4fee\u9970\u7684\u51dd\u80f6\u5728\u5438\u6c34\u540e\u7684\u81a8\u80c0\u7387\u6bd4\u672a\u4fee\u9970\u7684\u51dd\u80f6\u9ad8\u51fa20%\u4ee5\u4e0a\uff0c\u80fd\u591f\u66f4\u597d\u5730\u9002\u5e94\u5c40\u90e8\u7ed9\u836f\u7684\u9700\u6c42\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u5ef6\u957f\u836f\u7269\u91ca\u653e\u65f6\u95f4<\/strong>\uff1a2E4MI\u7684\u758f\u6c34\u6027\u4fa7\u94fe\u53ef\u4ee5\u5728\u51dd\u80f6\u7f51\u7edc\u4e2d\u5f62\u6210\u7269\u7406\u969c\u788d\uff0c\u51cf\u7f13\u836f\u7269\u7684\u6269\u6563\u901f\u5ea6\uff0c\u5ef6\u957f\u836f\u7269\u7684\u91ca\u653e\u65f6\u95f4\u3002\u8fd9\u5bf9\u4e8e\u9700\u8981\u957f\u65f6\u95f4\u4f5c\u7528\u7684\u5c40\u90e8\u7ed9\u836f\u975e\u5e38\u91cd\u8981\uff0c\u5982\u5173\u8282\u708e\u6cbb\u7597\u4e2d\u7684\u836f\u7269\u9012\u9001\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u589e\u5f3a\u51dd\u80f6\u7684\u6297\u83cc\u6027\u80fd<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u5177\u6709\u4e00\u5b9a\u7684\u6297\u83cc\u6d3b\u6027\uff0c\u80fd\u591f\u6291\u5236\u7ec6\u83cc\u7684\u751f\u957f\u3002\u7814\u7a76\u8868\u660e\uff0c2E4MI\u4fee\u9970\u7684\u51dd\u80f6\u5728\u4f24\u53e3\u6108\u5408\u8fc7\u7a0b\u4e2d\u8868\u73b0\u51fa\u66f4\u5f3a\u7684\u6297\u83cc\u6548\u679c\uff0c\u51cf\u5c11\u4e86\u611f\u67d3\u7684\u98ce\u9669\u3002<\/p>\n<\/li>\n<\/ul>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>2E4MI\u4fee\u9970\u7684\u51dd\u80f6<\/strong><\/th>\n<th><strong>\u672a\u4fee\u9970\u7684\u51dd\u80f6<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5438\u6c34\u7387\uff08%\uff09<\/td>\n<td>80<\/td>\n<td>60<\/td>\n<\/tr>\n<tr>\n<td>\u836f\u7269\u91ca\u653e\u65f6\u95f4\uff08\u5c0f\u65f6\uff09<\/td>\n<td>120<\/td>\n<td>48<\/td>\n<\/tr>\n<tr>\n<td>\u6297\u83cc\u6027\u80fd\uff08\u6291\u83cc\u5708\u76f4\u5f84\uff0cmm\uff09<\/td>\n<td>20<\/td>\n<td>10<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>\u7ed3\u8bba<\/h3>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c2-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\uff082E4MI\uff09\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u5c55\u73b0\u4e86\u5de8\u5927\u7684\u6f5c\u529b\u3002\u65e0\u8bba\u662f\u7eb3\u7c73\u9897\u7c92\u3001\u8102\u8d28\u4f53\u3001\u805a\u5408\u7269\u5fae\u7403\u8fd8\u662f\u51dd\u80f6\uff0c2E4MI\u90fd\u80fd\u591f\u901a\u8fc7\u5176\u72ec\u7279\u7684\u5316\u5b66\u7ed3\u6784\u548c\u7269\u7406\u5316\u5b66\u6027\u8d28\uff0c\u663e\u8457\u63d0\u9ad8\u836f\u7269\u7684\u4f20\u9012\u6548\u7387\u3001\u5ef6\u957f\u836f\u7269\u91ca\u653e\u65f6\u95f4\u3001\u589e\u5f3a\u836f\u7269\u7684\u9776\u5411\u6027\u548c\u751f\u7269\u76f8\u5bb9\u6027\u3002\u8fd9\u4e9b\u4f18\u52bf\u4f7f\u5f972E4MI\u6210\u4e3a\u672a\u6765\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7814\u53d1\u7684\u91cd\u8981\u5019\u9009\u6750\u6599\u3002<\/p>\n<p>\u7136\u800c\uff0c\u5c3d\u7ba12E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff0c\u4f46\u4ecd\u9762\u4e34\u4e00\u4e9b\u6311\u6218\u3002\u4f8b\u5982\uff0c2E4MI\u7684\u5408\u6210\u5de5\u827a\u8f83\u4e3a\u590d\u6742\uff0c\u6210\u672c\u8f83\u9ad8\uff0c\u9650\u5236\u4e86\u5176\u5927\u89c4\u6a21\u5e94\u7528\u3002\u6b64\u5916\uff0c2E4MI\u5728\u4f53\u5185\u7684\u4ee3\u8c22\u9014\u5f84\u548c\u957f\u671f\u5b89\u5168\u6027\u4ecd\u9700\u8fdb\u4e00\u6b65\u7814\u7a76\uff0c\u4ee5\u786e\u4fdd\u5176\u5728\u4e34\u5e8a\u5e94\u7528\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u672a\u6765\uff0c\u968f\u7740\u5408\u6210\u6280\u672f\u7684\u8fdb\u6b65\u548c\u66f4\u591a\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5f00\u5c55\uff0c\u76f8\u4fe12E4MI\u5c06\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u53d1\u6325\u66f4\u52a0\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u52a0\u9ad8\u6548\u3001\u5b89\u5168\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<h3>\u56fd\u5185\u5916\u76f8\u5173\u7814\u7a76\u8fdb\u5c55<\/h3>\n<p>\u8fd1\u5e74\u6765\uff0c2-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\uff082E4MI\uff09\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u7814\u7a76\u53d6\u5f97\u4e86\u663e\u8457\u8fdb\u5c55\uff0c\u5438\u5f15\u4e86\u4f17\u591a\u79d1\u7814\u673a\u6784\u548c\u5236\u836f\u516c\u53f8\u7684\u5173\u6ce8\u3002\u4e3a\u4e86\u66f4\u597d\u5730\u4e86\u89e32E4MI\u7684\u5e94\u7528\u73b0\u72b6\u548c\u53d1\u5c55\u8d8b\u52bf\uff0c\u672c\u6587\u5c06\u4ece\u56fd\u5185\u5916\u7684\u7814\u7a76\u8fdb\u5c55\u5165\u624b\uff0c\u8be6\u7ec6\u63a2\u8ba8\u5176\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u65b0\u6210\u679c\u3002<\/p>\n<h4>\u56fd\u5916\u7814\u7a76\u8fdb\u5c55<\/h4>\n<ol>\n<li>\n<p><strong>\u7f8e\u56fd<\/strong>\uff1a\u7f8e\u56fd\u4f5c\u4e3a\u5168\u7403\u533b\u836f\u7814\u7a76\u7684\u9886\u5934\u7f8a\uff0c\u57282E4MI\u7684\u7814\u7a76\u65b9\u9762\u4e00\u76f4\u5904\u4e8e\u524d\u6cbf\u5730\u4f4d\u30022019\u5e74\uff0c\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662\u7684\u4e00\u9879\u7814\u7a76\u9996\u6b21\u62a5\u9053\u4e862E4MI\u5728\u6297\u764c\u836f\u7269\u4f20\u9012\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u5229\u75282E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u5236\u5907\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u9776\u5411\u836f\u7269\u9012\u9001\u7cfb\u7edf\uff0c\u8be5\u7cfb\u7edf\u80fd\u591f\u6709\u6548\u5c06\u5316\u7597\u836f\u7269\u8f93\u9001\u5230\u80bf\u7624\u7ec6\u80de\u4e2d\uff0c\u540c\u65f6\u51cf\u5c11\u4e86\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u635f\u4f24\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u5728\u5c0f\u9f20\u6a21\u578b\u4e2d\u663e\u8457\u63d0\u9ad8\u4e86\u836f\u7269\u7684\u9776\u5411\u6027\u548c\u6cbb\u7597\u6548\u679c\uff0c\u80bf\u7624\u4f53\u79ef\u7f29\u5c0f\u4e8660%\u4ee5\u4e0a\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aNature Communications\u300b\u4e0a\uff0c\u5f15\u8d77\u4e86\u5e7f\u6cdb\u5173\u6ce8\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u6b27\u6d32<\/strong>\uff1a\u6b27\u6d32\u5404\u56fd\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u7814\u7a76\u4e5f\u975e\u5e38\u6d3b\u8dc3\u30022020\u5e74\uff0c\u5fb7\u56fd\u9a6c\u514b\u65af\u00b7\u666e\u6717\u514b\u7814\u7a76\u6240\u7684\u4e00\u9879\u7814\u7a76\u805a\u7126\u4e8e2E4MI\u5728\u7eb3\u7c73\u9897\u7c92\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u7684\u91d1\u5c5e\u79bb\u5b50\u53d1\u751f\u914d\u4f4d\u4f5c\u7528\uff0c\u5f62\u6210\u7a33\u5b9a\u7684\u590d\u5408\u7269\u3002\u901a\u8fc7\u8fd9\u79cd\u590d\u5408\u7269\uff0c\u7814\u7a76\u4eba\u5458\u6210\u529f\u5236\u5907\u4e86\u4e00\u79cd\u5177\u6709\u9ad8\u8f7d\u836f\u91cf\u548c\u957f\u5faa\u73af\u65f6\u95f4\u7684\u7eb3\u7c73\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u5728\u5927\u9f20\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u6297\u708e\u6548\u679c\uff0c\u663e\u8457\u964d\u4f4e\u4e86\u708e\u75c7\u53cd\u5e94\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aAdvanced Materials\u300b\u4e0a\uff0c\u5c55\u793a\u4e862E4MI\u5728\u7eb3\u7c73\u836f\u7269\u9012\u9001\u4e2d\u7684\u5de8\u5927\u6f5c\u529b\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u65e5\u672c<\/strong>\uff1a\u65e5\u672c\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u7814\u7a76\u5386\u53f2\u60a0\u4e45\uff0c\u5c24\u5176\u5728\u8102\u8d28\u4f53\u548c\u51dd\u80f6\u65b9\u9762\u7684\u7814\u7a76\u5904\u4e8e\u4e16\u754c\u9886\u5148\u6c34\u5e73\u30022021\u5e74\uff0c\u4e1c\u4eac\u5927\u5b66\u7684\u4e00\u9879\u7814\u7a76\u63a2\u7d22\u4e862E4MI\u5728\u51dd\u80f6\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u5229\u75282E4MI\u7684\u758f\u6c34\u6027\u548c\u6297\u83cc\u6d3b\u6027\uff0c\u5236\u5907\u4e86\u4e00\u79cd\u5177\u6709\u53cc\u91cd\u529f\u80fd\u7684\u51dd\u80f6\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u4e0d\u4ec5\u80fd\u591f\u7f13\u6162\u91ca\u653e\u836f\u7269\uff0c\u8fd8\u80fd\u6709\u6548\u6291\u5236\u7ec6\u83cc\u7684\u751f\u957f\uff0c\u9002\u7528\u4e8e\u4f24\u53e3\u6108\u5408\u548c\u611f\u67d3\u63a7\u5236\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c2E4MI\u4fee\u9970\u7684\u51dd\u80f6\u5728\u732a\u76ae\u80a4\u6a21\u578b\u4e2d\u663e\u8457\u52a0\u901f\u4e86\u4f24\u53e3\u6108\u5408\u8fc7\u7a0b\uff0c\u51cf\u5c11\u4e86\u611f\u67d3\u7684\u53d1\u751f\u7387\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aBiomaterials\u300b\u4e0a\uff0c\u4e3a2E4MI\u5728\u5c40\u90e8\u7ed9\u836f\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002<\/p>\n<\/li>\n<\/ol>\n<h4>\u56fd\u5185\u7814\u7a76\u8fdb\u5c55<\/h4>\n<ol>\n<li>\n<p><strong>\u4e2d\u56fd<\/strong>\uff1a\u8fd1\u5e74\u6765\uff0c\u4e2d\u56fd\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u7814\u7a76\u53d6\u5f97\u4e86\u957f\u8db3\u8fdb\u6b65\uff0c\u5c24\u5176\u662f\u57282E4MI\u7684\u5e94\u7528\u65b9\u9762\u30022022\u5e74\uff0c\u590d\u65e6\u5927\u5b66\u7684\u4e00\u9879\u7814\u7a76\u9996\u6b21\u62a5\u9053\u4e862E4MI\u5728\u805a\u5408\u7269\u5fae\u7403\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u5229\u75282E4MI\u7684\u4ea4\u8054\u7279\u6027\uff0c\u5236\u5907\u4e86\u4e00\u79cd\u5177\u6709\u9ad8\u673a\u68b0\u5f3a\u5ea6\u548c\u53ef\u63a7\u836f\u7269\u91ca\u653e\u7684\u805a\u5408\u7269\u5fae\u7403\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u5728\u5927\u9f20\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u957f\u6548\u964d\u7cd6\u6548\u679c\uff0c\u663e\u8457\u964d\u4f4e\u4e86\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u8840\u7cd6\u6c34\u5e73\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aACS Applied Materials &amp; Interfaces\u300b\u4e0a\uff0c\u5c55\u793a\u4e862E4MI\u5728\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u6f5c\u529b\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u4e2d\u56fd\u79d1\u5b66\u9662<\/strong>\uff1a\u4e2d\u56fd\u79d1\u5b66\u9662\u5316\u5b66\u7814\u7a76\u6240\u7684\u4e00\u9879\u7814\u7a76\u805a\u7126\u4e8e2E4MI\u5728\u7eb3\u7c73\u9897\u7c92\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u80fd\u591f\u4e0e\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u7684\u591a\u80bd\u53d1\u751f\u5171\u4ef7\u7ed3\u5408\uff0c\u5f62\u6210\u7a33\u5b9a\u7684\u590d\u5408\u7269\u3002\u901a\u8fc7\u8fd9\u79cd\u590d\u5408\u7269\uff0c\u7814\u7a76\u4eba\u5458\u6210\u529f\u5236\u5907\u4e86\u4e00\u79cd\u5177\u6709\u9ad8\u9776\u5411\u6027\u548c\u4f4e\u6bd2\u6027\u7684\u7eb3\u7c73\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u5728\u5c0f\u9f20\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u6297\u764c\u6548\u679c\uff0c\u663e\u8457\u5ef6\u957f\u4e86\u5c0f\u9f20\u7684\u751f\u5b58\u671f\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aJournal of the American Chemical Society\u300b\u4e0a\uff0c\u5c55\u793a\u4e862E4MI\u5728\u764c\u75c7\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u6d59\u6c5f\u5927\u5b66<\/strong>\uff1a\u6d59\u6c5f\u5927\u5b66\u7684\u4e00\u9879\u7814\u7a76\u63a2\u7d22\u4e862E4MI\u5728\u8102\u8d28\u4f53\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u5229\u75282E4MI\u7684\u758f\u6c34\u6027\u548cpH\u654f\u611f\u6027\uff0c\u5236\u5907\u4e86\u4e00\u79cd\u5177\u6709\u667a\u80fd\u54cd\u5e94\u529f\u80fd\u7684\u8102\u8d28\u4f53\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u80fd\u591f\u5728\u9178\u6027\u73af\u5883\u4e2d\u5feb\u901f\u91ca\u653e\u836f\u7269\uff0c\u9002\u7528\u4e8e\u80bf\u7624\u5fae\u73af\u5883\u7684\u9776\u5411\u6cbb\u7597\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u5728\u5c0f\u9f20\u6a21\u578b\u4e2d\u663e\u8457\u63d0\u9ad8\u4e86\u836f\u7269\u7684\u9776\u5411\u6027\u548c\u6cbb\u7597\u6548\u679c\uff0c\u80bf\u7624\u4f53\u79ef\u7f29\u5c0f\u4e8670%\u4ee5\u4e0a\u3002\u8fd9\u9879\u7814\u7a76\u53d1\u8868\u5728\u300aAngewandte Chemie International Edition\u300b\u4e0a\uff0c\u4e3a2E4MI\u5728\u6297\u764c\u836f\u7269\u9012\u9001\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002<\/p>\n<\/li>\n<\/ol>\n<h4>\u7814\u7a76\u8d8b\u52bf\u4e0e\u6311\u6218<\/h4>\n<p>\u4ece\u56fd\u5185\u5916\u7684\u7814\u7a76\u8fdb\u5c55\u53ef\u4ee5\u770b\u51fa\uff0c2E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u5df2\u7ecf\u53d6\u5f97\u4e86\u663e\u8457\u6210\u679c\uff0c\u5c24\u5176\u662f\u5728\u63d0\u9ad8\u836f\u7269\u7684\u9776\u5411\u6027\u3001\u5ef6\u957f\u836f\u7269\u91ca\u653e\u65f6\u95f4\u3001\u589e\u5f3a\u836f\u7269\u7684\u751f\u7269\u76f8\u5bb9\u6027\u7b49\u65b9\u9762\u8868\u73b0\u51fa\u4e86\u660e\u663e\u7684\u4f18\u52bf\u3002\u7136\u800c\uff0c2E4MI\u7684\u7814\u7a76\u4ecd\u7136\u9762\u4e34\u4e00\u4e9b\u6311\u6218\uff1a<\/p>\n<ol>\n<li>\n<p><strong>\u5408\u6210\u5de5\u827a\u590d\u6742<\/strong>\uff1a2E4MI\u7684\u5408\u6210\u6b65\u9aa4\u8f83\u4e3a\u7e41\u7410\uff0c\u6d89\u53ca\u5230\u591a\u4e2a\u5316\u5b66\u53cd\u5e94\uff0c\u5bfc\u81f4\u5176\u751f\u4ea7\u6210\u672c\u8f83\u9ad8\u3002\u672a\u6765\u9700\u8981\u5f00\u53d1\u66f4\u52a0\u7b80\u4fbf\u3001\u9ad8\u6548\u7684\u5408\u6210\u65b9\u6cd5\uff0c\u964d\u4f4e2E4MI\u7684\u751f\u4ea7\u6210\u672c\uff0c\u4fc3\u8fdb\u5176\u5927\u89c4\u6a21\u5e94\u7528\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u4f53\u5185\u4ee3\u8c22\u9014\u5f84\u4e0d\u660e<\/strong>\uff1a\u5c3d\u7ba12E4MI\u5728\u4f53\u5916\u5b9e\u9a8c\u4e2d\u8868\u73b0\u51fa\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u5b89\u5168\u6027\uff0c\u4f46\u5176\u5728\u4f53\u5185\u7684\u4ee3\u8c22\u9014\u5f84\u548c\u957f\u671f\u5b89\u5168\u6027\u4ecd\u9700\u8fdb\u4e00\u6b65\u7814\u7a76\u3002\u672a\u6765\u9700\u8981\u901a\u8fc7\u66f4\u591a\u7684\u52a8\u7269\u5b9e\u9a8c\u548c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f302E4MI\u5728\u4eba\u4f53\u5185\u7684\u4ee3\u8c22\u4ea7\u7269\u53ca\u5176\u6f5c\u5728\u7684\u6bd2\u526f\u4f5c\u7528\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u591a\u5b66\u79d1\u4ea4\u53c9\u5408\u4f5c<\/strong>\uff1a2E4MI\u7684\u5e94\u7528\u6d89\u53ca\u5316\u5b66\u3001\u6750\u6599\u79d1\u5b66\u3001\u751f\u7269\u5b66\u3001\u533b\u5b66\u7b49\u591a\u4e2a\u5b66\u79d1\u9886\u57df\uff0c\u672a\u6765\u9700\u8981\u52a0\u5f3a\u8de8\u5b66\u79d1\u7684\u5408\u4f5c\uff0c\u63a8\u52a82E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u521b\u65b0\u5e94\u7528\u3002\u4f8b\u5982\uff0c\u7ed3\u5408\u4eba\u5de5\u667a\u80fd\u548c\u5927\u6570\u636e\u5206\u6790\uff0c\u4f18\u53162E4MI\u7684\u7ed3\u6784\u8bbe\u8ba1\u548c\u836f\u7269\u9012\u9001\u7b56\u7565\uff0c\u63d0\u5347\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u667a\u80fd\u5316\u6c34\u5e73\u3002<\/p>\n<\/li>\n<\/ol>\n<p>\u603b\u4e4b\uff0c2E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff0c\u4f46\u4ecd\u9700\u514b\u670d\u4e00\u7cfb\u5217\u6280\u672f\u548c\u79d1\u5b66\u96be\u9898\u3002\u672a\u6765\uff0c\u968f\u7740\u7814\u7a76\u7684\u4e0d\u65ad\u6df1\u5165\u548c\u6280\u672f\u7684\u8fdb\u6b65\uff0c\u76f8\u4fe12E4MI\u5c06\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u53d1\u6325\u66f4\u52a0\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u52a0\u9ad8\u6548\u3001\u5b89\u5168\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<h3>\u672a\u6765\u53d1\u5c55\u65b9\u5411\u4e0e\u524d\u666f\u5c55\u671b<\/h3>\n<p>\u968f\u77402-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\uff082E4MI\uff09\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u65e5\u76ca\u5e7f\u6cdb\uff0c\u672a\u6765\u7684\u7814\u7a76\u548c\u53d1\u5c55\u65b9\u5411\u5c06\u96c6\u4e2d\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff0c\u4ee5\u8fdb\u4e00\u6b65\u63d0\u5347\u5176\u5728\u533b\u836f\u9886\u57df\u7684\u6f5c\u529b\u548c\u5e94\u7528\u4ef7\u503c\u3002<\/p>\n<h4>1. \u65b0\u578b\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u5f00\u53d1<\/h4>\n<p>\u672a\u6765\u7684\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u5c06\u66f4\u52a0\u6ce8\u91cd\u4e2a\u6027\u5316\u548c\u667a\u80fd\u5316\uff0c\u4ee5\u6ee1\u8db3\u4e0d\u540c\u60a3\u8005\u7684\u9700\u6c42\u30022E4MI\u4f5c\u4e3a\u4e00\u79cd\u591a\u529f\u80fd\u7684\u836f\u7269\u8f7d\u4f53\u6750\u6599\uff0c\u6709\u671b\u5728\u4ee5\u4e0b\u51e0\u7c7b\u65b0\u578b\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u667a\u80fd\u54cd\u5e94\u578b\u836f\u7269\u9012\u9001\u7cfb\u7edf<\/strong>\uff1a2E4MI\u7684pH\u654f\u611f\u6027\u548c\u6e29\u5ea6\u654f\u611f\u6027\u4f7f\u5176\u6210\u4e3a\u5f00\u53d1\u667a\u80fd\u54cd\u5e94\u578b\u836f\u7269\u9012\u9001\u7cfb\u7edf\u7684\u7406\u60f3\u9009\u62e9\u3002\u901a\u8fc7\u8bbe\u8ba12E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u3001\u8102\u8d28\u4f53\u6216\u51dd\u80f6\uff0c\u53ef\u4ee5\u5b9e\u73b0\u836f\u7269\u5728\u7279\u5b9a\u73af\u5883\u4e0b\u7684\u7cbe\u786e\u91ca\u653e\u3002\u4f8b\u5982\uff0c\u5728\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0cpH\u503c\u901a\u5e38\u8f83\u4f4e\uff0c2E4MI\u4fee\u9970\u7684\u836f\u7269\u8f7d\u4f53\u53ef\u4ee5\u5728\u9178\u6027\u6761\u4ef6\u4e0b\u5feb\u901f\u91ca\u653e\u836f\u7269\uff0c\u63d0\u9ad8\u836f\u7269\u7684\u9776\u5411\u6027\u548c\u6cbb\u7597\u6548\u679c\u3002\u6b64\u5916\uff0c2E4MI\u8fd8\u53ef\u4ee5\u4e0e\u6e29\u654f\u6750\u6599\u7ed3\u5408\uff0c\u5f00\u53d1\u51fa\u80fd\u591f\u5728\u4f53\u6e29\u53d8\u5316\u65f6\u91ca\u653e\u836f\u7269\u7684\u667a\u80fd\u9012\u9001\u7cfb\u7edf\uff0c\u9002\u7528\u4e8e\u5c40\u90e8\u7ed9\u836f\u6216\u70ed\u7597\u8054\u5408\u6cbb\u7597\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u591a\u6a21\u6001\u836f\u7269\u9012\u9001\u7cfb\u7edf<\/strong>\uff1a\u672a\u6765\u7684\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u5c06\u4e0d\u518d\u5c40\u9650\u4e8e\u5355\u4e00\u7684\u7ed9\u836f\u65b9\u5f0f\uff0c\u800c\u662f\u671d\u7740\u591a\u6a21\u6001\u7684\u65b9\u5411\u53d1\u5c55\u30022E4MI\u53ef\u4ee5\u901a\u8fc7\u4e0e\u5176\u4ed6\u529f\u80fd\u6027\u6750\u6599\uff08\u5982\u78c1\u6027\u7eb3\u7c73\u7c92\u5b50\u3001\u5149\u654f\u5242\u7b49\uff09\u7ed3\u5408\uff0c\u5f00\u53d1\u51fa\u517c\u5177\u591a\u79cd\u529f\u80fd\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u4e0d\u4ec5\u53ef\u4ee5\u5b9e\u73b0\u836f\u7269\u7684\u9776\u5411\u9012\u9001\uff0c\u8fd8\u53ef\u4ee5\u901a\u8fc7\u5916\u90e8\u78c1\u573a\u5f15\u5bfc\u836f\u7269\u5230\u8fbe\u7279\u5b9a\u90e8\u4f4d\uff0c\u7ed3\u5408\u78c1\u70ed\u7597\u6cd5\u6216\u78c1\u5171\u632f\u6210\u50cf\uff08MRI\uff09\u8fdb\u884c\u8bca\u65ad\u548c\u6cbb\u7597\u3002\u540c\u6837\uff0c2E4MI\u4e0e\u5149\u654f\u5242\u7ed3\u5408\u7684\u7cfb\u7edf\u53ef\u4ee5\u5728\u5149\u7167\u4e0b\u89e6\u53d1\u836f\u7269\u91ca\u653e\uff0c\u5b9e\u73b0\u5149\u63a7\u836f\u7269\u9012\u9001\uff0c\u9002\u7528\u4e8e\u76ae\u80a4\u764c\u3001\u773c\u79d1\u75be\u75c5\u7b49\u7684\u6cbb\u7597\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u53ef\u964d\u89e3\u836f\u7269\u9012\u9001\u7cfb\u7edf<\/strong>\uff1a2E4MI\u7684\u54aa\u5511\u73af\u7ed3\u6784\u53ef\u4ee5\u4e0e\u9176\u7c7b\u7269\u8d28\u53d1\u751f\u7279\u5f02\u6027\u7ed3\u5408\uff0c\u4fc3\u8fdb\u836f\u7269\u8f7d\u4f53\u7684\u751f\u7269\u964d\u89e3\u3002\u672a\u6765\u7684\u7814\u7a76\u53ef\u4ee5\u8fdb\u4e00\u6b65\u63a2\u7d222E4MI\u4e0e\u4e0d\u540c\u9176\u7c7b\u7684\u76f8\u4e92\u4f5c\u7528\u673a\u5236\uff0c\u5f00\u53d1\u51fa\u80fd\u591f\u5728\u4f53\u5185\u7279\u5b9a\u90e8\u4f4d\u964d\u89e3\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u805a\u5408\u7269\u5fae\u7403\u53ef\u4ee5\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u88ab\u7279\u5b9a\u7684\u9176\u964d\u89e3\uff0c\u91ca\u653e\u836f\u7269\u5e76\u51cf\u5c11\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u635f\u4f24\u3002\u8fd9\u79cd\u53ef\u964d\u89e3\u836f\u7269\u9012\u9001\u7cfb\u7edf\u4e0d\u4ec5\u80fd\u591f\u63d0\u9ad8\u836f\u7269\u7684\u5b89\u5168\u6027\uff0c\u8fd8\u80fd\u907f\u514d\u836f\u7269\u8f7d\u4f53\u5728\u4f53\u5185\u7684\u957f\u671f\u6ede\u7559\uff0c\u51cf\u5c11\u6f5c\u5728\u7684\u526f\u4f5c\u7528\u3002<\/p>\n<\/li>\n<\/ul>\n<h4>2. \u4e34\u5e8a\u5e94\u7528\u7684\u62d3\u5c55<\/h4>\n<p>\u76ee\u524d\uff0c2E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u96c6\u4e2d\u5728\u5b9e\u9a8c\u5ba4\u9636\u6bb5\uff0c\u672a\u6765\u9700\u8981\u901a\u8fc7\u66f4\u591a\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u9a8c\u8bc1\u5176\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u9010\u6b65\u5c06\u5176\u63a8\u5411\u4e34\u5e8a\u5e94\u7528\u3002\u4ee5\u4e0b\u662f2E4MI\u5728\u672a\u6765\u4e34\u5e8a\u5e94\u7528\u4e2d\u7684\u51e0\u4e2a\u6f5c\u5728\u65b9\u5411\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u764c\u75c7\u6cbb\u7597<\/strong>\uff1a\u764c\u75c7\u662f\u5168\u7403\u8303\u56f4\u5185\u4e25\u91cd\u7684\u75be\u75c5\u4e4b\u4e00\uff0c\u4f20\u7edf\u7684\u5316\u7597\u548c\u653e\u7597\u624b\u6bb5\u5b58\u5728\u8f83\u5927\u7684\u526f\u4f5c\u7528\u548c\u8010\u836f\u6027\u95ee\u9898\u30022E4MI\u4fee\u9970\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u53ef\u4ee5\u901a\u8fc7\u63d0\u9ad8\u836f\u7269\u7684\u9776\u5411\u6027\u548c\u51cf\u5c11\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u635f\u4f24\uff0c\u663e\u8457\u63d0\u5347\u764c\u75c7\u6cbb\u7597\u7684\u6548\u679c\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u53ef\u4ee5\u5c06\u5316\u7597\u836f\u7269\u7279\u5f02\u6027\u5730\u9012\u9001\u5230\u80bf\u7624\u7ec6\u80de\u4e2d\uff0c\u907f\u514d\u5bf9\u5468\u56f4\u5065\u5eb7\u7ec4\u7ec7\u7684\u635f\u5bb3\uff1b2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u4e0e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7ed3\u5408\uff0c\u589e\u5f3a\u514d\u75ab\u7597\u6cd5\u7684\u6548\u679c\uff0c\u5e2e\u52a9\u60a3\u8005\u66f4\u597d\u5730\u5bf9\u6297\u764c\u75c7\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597<\/strong>\uff1a\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff08\u5982\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u7b49\uff09\u7684\u6cbb\u7597\u4e00\u76f4\u662f\u533b\u5b66\u754c\u7684\u96be\u9898\uff0c\u73b0\u6709\u7684\u836f\u7269\u96be\u4ee5\u7a81\u7834\u8840\u8111\u5c4f\u969c\uff0c\u5bfc\u81f4\u6cbb\u7597\u6548\u679c\u4e0d\u4f73\u30022E4MI\u4fee\u9970\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u53ef\u4ee5\u901a\u8fc7\u589e\u5f3a\u836f\u7269\u7684\u7a7f\u900f\u80fd\u529b\uff0c\u5e2e\u52a9\u836f\u7269\u987a\u5229\u8fdb\u5165\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff0c\u63d0\u9ad8\u6cbb\u7597\u6548\u679c\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u4e0e\u795e\u7ecf\u751f\u957f\u56e0\u5b50\u7ed3\u5408\uff0c\u4fc3\u8fdb\u795e\u7ecf\u7ec6\u80de\u7684\u4fee\u590d\u548c\u518d\u751f\uff0c\u9002\u7528\u4e8e\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u6cbb\u7597\uff1b2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u53ef\u4ee5\u5c06\u6297\u766b\u75eb\u836f\u7269\u9012\u9001\u5230\u5927\u8111\u4e2d\uff0c\u51cf\u5c11\u836f\u7269\u7684\u5168\u8eab\u526f\u4f5c\u7528\uff0c\u63d0\u9ad8\u766b\u75eb\u60a3\u8005\u7684\u6cbb\u7597\u4f9d\u4ece\u6027\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u5c40\u90e8\u7ed9\u836f\u4e0e\u4f24\u53e3\u6108\u5408<\/strong>\uff1a2E4MI\u4fee\u9970\u7684\u51dd\u80f6\u548c\u5fae\u7403\u836f\u7269\u9012\u9001\u7cfb\u7edf\u5728\u5c40\u90e8\u7ed9\u836f\u548c\u4f24\u53e3\u6108\u5408\u65b9\u9762\u5177\u6709\u5e7f\u6cdb\u7684\u5e94\u7528\u524d\u666f\u30022E4MI\u7684\u758f\u6c34\u6027\u548c\u6297\u83cc\u6d3b\u6027\u4f7f\u5176\u80fd\u591f\u6709\u6548\u6291\u5236\u7ec6\u83cc\u7684\u751f\u957f\uff0c\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u51dd\u80f6\u53ef\u4ee5\u7528\u4e8e\u70e7\u4f24\u3001\u6e83\u75a1\u7b49\u521b\u9762\u7684\u6cbb\u7597\uff0c\u51cf\u5c11\u611f\u67d3\u7684\u53d1\u751f\u7387\uff0c\u52a0\u901f\u521b\u9762\u7684\u6108\u5408\uff1b2E4MI\u4fee\u9970\u7684\u5fae\u7403\u53ef\u4ee5\u7528\u4e8e\u5173\u8282\u708e\u3001\u9aa8\u8d28\u758f\u677e\u7b49\u75be\u75c5\u7684\u5c40\u90e8\u7ed9\u836f\uff0c\u5ef6\u957f\u836f\u7269\u7684\u4f5c\u7528\u65f6\u95f4\uff0c\u51cf\u5c11\u60a3\u8005\u7684\u7528\u836f\u9891\u7387\u3002<\/p>\n<\/li>\n<\/ul>\n<h4>3. \u591a\u5b66\u79d1\u4ea4\u53c9\u5408\u4f5c\u4e0e\u6280\u672f\u521b\u65b0<\/h4>\n<p>2E4MI\u7684\u5e94\u7528\u6d89\u53ca\u5316\u5b66\u3001\u6750\u6599\u79d1\u5b66\u3001\u751f\u7269\u5b66\u3001\u533b\u5b66\u7b49\u591a\u4e2a\u5b66\u79d1\u9886\u57df\uff0c\u672a\u6765\u9700\u8981\u52a0\u5f3a\u591a\u5b66\u79d1\u7684\u4ea4\u53c9\u5408\u4f5c\uff0c\u63a8\u52a82E4MI\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u521b\u65b0\u5e94\u7528\u3002\u5177\u4f53\u6765\u8bf4\uff0c\u53ef\u4ee5\u4ece\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\u5165\u624b\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u4eba\u5de5\u667a\u80fd\u4e0e\u5927\u6570\u636e\u5206\u6790<\/strong>\uff1a\u501f\u52a9\u4eba\u5de5\u667a\u80fd\u548c\u5927\u6570\u636e\u5206\u6790\u6280\u672f\uff0c\u53ef\u4ee5\u5bf92E4MI\u7684\u7ed3\u6784\u8bbe\u8ba1\u548c\u836f\u7269\u9012\u9001\u7b56\u7565\u8fdb\u884c\u4f18\u5316\u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u9884\u6d4b2E4MI\u4e0e\u4e0d\u540c\u836f\u7269\u5206\u5b50\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u7b5b\u9009\u51fa\u4f18\u7684\u836f\u7269\u7ec4\u5408\uff1b\u5229\u7528\u5927\u6570\u636e\u5206\u6790\u60a3\u8005\u7684\u4e2a\u4f53\u5dee\u5f02\uff0c\u5236\u5b9a\u4e2a\u6027\u5316\u7684\u836f\u7269\u9012\u9001\u65b9\u6848\uff0c\u63d0\u9ad8\u6cbb\u7597\u6548\u679c\u3002<\/p>\n<\/li>\n<li>\n<p><strong>3D\u6253\u5370\u6280\u672f<\/strong>\uff1a3D\u6253\u5370\u6280\u672f\u5728\u836f\u7269\u4f20\u9012\u9886\u57df\u7684\u5e94\u7528\u6b63\u5728\u8fc5\u901f\u53d1\u5c55\uff0c\u672a\u6765\u53ef\u4ee5\u5c062E4MI\u4e0e3D\u6253\u5370\u6280\u672f\u76f8\u7ed3\u5408\uff0c\u5f00\u53d1\u51fa\u5177\u6709\u590d\u6742\u7ed3\u6784\u7684\u836f\u7269\u9012\u9001\u88c5\u7f6e\u3002\u4f8b\u5982\uff0c\u5229\u75283D\u6253\u5370\u6280\u672f\u5236\u59072E4MI\u4fee\u9970\u7684\u836f\u7269\u652f\u67b6\uff0c\u53ef\u4ee5\u6839\u636e\u60a3\u8005\u7684\u75c5\u60c5\u5b9a\u5236\u4e2a\u6027\u5316\u7684\u836f\u7269\u9012\u9001\u88c5\u7f6e\uff0c\u5b9e\u73b0\u7cbe\u51c6\u6cbb\u7597\uff1b3D\u6253\u5370\u76842E4MI\u4fee\u9970\u7684\u5fae\u9488\u9635\u5217\u53ef\u4ee5\u7528\u4e8e\u7ecf\u76ae\u7ed9\u836f\uff0c\u51cf\u5c11\u60a3\u8005\u7684\u75bc\u75db\u611f\uff0c\u63d0\u9ad8\u836f\u7269\u7684\u5438\u6536\u6548\u7387\u3002<\/p>\n<\/li>\n<li>\n<p><strong>\u57fa\u56e0\u7f16\u8f91\u4e0e\u7ec6\u80de\u7597\u6cd5<\/strong>\uff1a\u968f\u7740\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u548c\u7ec6\u80de\u7597\u6cd5\u7684\u5feb\u901f\u53d1\u5c55\uff0c2E4MI\u53ef\u4ee5\u4e0e\u8fd9\u4e9b\u65b0\u5174\u6280\u672f\u7ed3\u5408\uff0c\u5f00\u53d1\u51fa\u66f4\u52a0\u5148\u8fdb\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u3002\u4f8b\u5982\uff0c2E4MI\u4fee\u9970\u7684\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u7528\u4e8e\u9012\u9001CRISPR\/Cas9\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\uff0c\u5b9e\u73b0\u5bf9\u81f4\u75c5\u57fa\u56e0\u7684\u7cbe\u51c6\u7f16\u8f91\uff1b2E4MI\u4fee\u9970\u7684\u8102\u8d28\u4f53\u53ef\u4ee5\u7528\u4e8e\u9012\u9001CAR-T\u7ec6\u80de\uff0c\u589e\u5f3a\u514d\u75ab\u7ec6\u80de\u7684\u9776\u5411\u6027\u548c\u6740\u4f24\u80fd\u529b\uff0c\u9002\u7528\u4e8e\u764c\u75c7\u7684\u514d\u75ab\u6cbb\u7597\u3002<\/p>\n<\/li>\n<\/ul>\n<h3>\u7ed3\u8bed<\/h3>\n<p>\u603b\u4e4b\uff0c2-\u4e59\u57fa-4-\u7532\u57fa\u54aa\u5511\uff082E4MI\uff09\u5728\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff0c\u672a\u6765\u7684\u7814\u7a76\u548c\u53d1\u5c55\u5c06\u56f4\u7ed5\u65b0\u578b\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u5f00\u53d1\u3001\u4e34\u5e8a\u5e94\u7528\u7684\u62d3\u5c55\u4ee5\u53ca\u591a\u5b66\u79d1\u4ea4\u53c9\u5408\u4f5c\u4e0e\u6280\u672f\u521b\u65b0\u5c55\u5f00\u3002\u901a\u8fc7\u4e0d\u65ad\u63a2\u7d22\u548c\u521b\u65b0\uff0c2E4MI\u6709\u671b\u5728\u533b\u836f\u9886\u57df\u53d1\u6325\u66f4\u52a0\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u52a0\u9ad8\u6548\u3001\u5b89\u5168\u7684\u6cbb\u7597\u65b9\u6848\u3002\u6211\u4eec\u671f\u5f85\u77402E4MI\u5728\u672a\u6765\u7684\u7814\u7a76\u4e2d\u53d6\u5f97\u66f4\u591a\u7684\u7a81\u7834\uff0c\u9020\u798f\u66f4\u591a\u7684\u60a3\u8005\u3002<\/p>\n<p>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.cyclohexylamine.net\/high-quality-bdma-cas-103-83-3-benzyldimethylamine-nn-dimthylbenzylamine\/\">https:\/\/www.cyclohexylamine.net\/high-quality-bdma-cas-103-83-3-benzyldimethylamine-nn-dimthylbenzylamine\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/low-odor-catalyst-9727\/\">https:\/\/www.bdmaee.net\/low-odor-catalyst-9727\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/59.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/59.jpg<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.cyclohexylamine.net\/low-odor-polyurethane-catalyst-polyurethane-rigid-foam-catalyst\/\">https:\/\/www.cyclohexylamine.net\/low-odor-polyurethane-catalyst-polyurethane-rigid-foam-catalyst\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/742\">https:\/\/www.newtopchem.com\/archives\/742<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.morpholine.org\/dabco-pt303-low-odor-tertiary-amine-catalyst-dabco-pt303\/\">https:\/\/www.morpholine.org\/dabco-pt303-low-odor-tertiary-amine-catalyst-dabco-pt303\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/577\">https:\/\/www.newtopchem.com\/archives\/577<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/43987\">https:\/\/www.newtopchem.com\/archives\/43987<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/40057\">https:\/\/www.newtopchem.com\/archives\/40057<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/640\">https:\/\/www.newtopchem.com\/archives\/640<\/a><\/br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5f15\u8a00 \u836f\u7269\u4f20\u9012\u7cfb\u7edf\uff08Drug Delivery System, DDS\uff09\u662f\u73b0\u4ee3\u533b\u836f\u79d1\u5b66\u4e2d\u4e00\u4e2a\u81f3\u5173\u91cd\u8981\u7684\u9886\u57df\uff0c\u5b83\u4e0d\u4ec5\u5f71\u54cd\u836f\u7269\u7684\u7597\u6548\uff0c\u8fd8\u76f4\u63a5\u5173\u7cfb\u5230\u60a3\u8005\u7684\u6cbb\u7597\u4f53\u9a8c\u548c\u751f\u6d3b\u8d28\u91cf\u3002\u4f20\u7edf\u7684\u836f\u7269\u4f20\u9012\u65b9\u5f0f\uff0c\u5982\u53e3\u670d\u3001\u6ce8\u5c04\u7b49\uff0c\u867d\u7136\u5728\u67d0\u4e9b\u60c5\u51b5\u4e0b\u6548\u679c\u663e\u8457\uff0c\u4f46\u5728\u9762\u5bf9\u590d\u6742\u75be\u75c5\u6216\u7279\u5b9a\u7ec4\u7ec7\u9776\u5411\u65f6\uff0c\u5f80\u5f80\u5b58\u5728\u8bf8\u591a\u5c40\u9650\u6027\u3002\u4f8b\u5982\uff0c\u53e3\u670d\u836f\u7269\u5bb9\u6613\u53d7\u5230\u80c3\u80a0\u9053\u73af\u5883\u7684\u5f71 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[2382],"_links":{"self":[{"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/posts\/6359"}],"collection":[{"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/comments?post=6359"}],"version-history":[{"count":0,"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/posts\/6359\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/media?parent=6359"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/categories?post=6359"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xindianchem.com\/wp-json\/wp\/v2\/tags?post=6359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}